(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one - Names and Identifiers
Name | 2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-
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Synonyms | Indacaterol Impurity 8 Indacaterol Intermediate (R)-8-benzyloxy-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin- (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1 (R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one (R)-8-(benzyloxy)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylaMino)-1-hydroxyethyl)quinolin-2(1H)-one (R)-8-(benzyloxy)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylamino)-1-hydroxyethyl)quinolin-2(1H)-one 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one (R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one 2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-
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CAS | 435273-75-9
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(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one - Physico-chemical Properties
Molecular Formula | C31H34N2O3
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Molar Mass | 482.61 |
Density | 1.23 |
Melting Point | 78-82°C |
Boling Point | 734.1±60.0 °C(Predicted) |
Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Off-White to Pale Yellow |
pKa | 10.86±0.70(Predicted) |
Storage Condition | -20°C Freezer |
(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one - Introduction
2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2, 3-dihydroxy-1H-inden-2-yl) amino]-1-hydroxyethyl]-8-(phenylmethoxy)-, also known as 2(1H)-quinolinone, 5-[(1R)-2-[(5,6-diethyl-2, 3-Dihydro-1H-inden-2-yl) amino]-1-hydroxyethyl]-8-(benzyloxy)-.
The properties of this compound are as follows:
-Molecular formula: C31H38N2O2
-Molecular weight: 470.65g/mol
-Appearance: white or off-white crystalline solid
-Melting point: about 128-130°C
-Solubility: Soluble in some organic solvents, such as methanol and dichloromethane, poor solubility in water.
Use of this compound:
-is a pharmaceutical intermediate that can play an important role in the synthesis of biologically active compounds.
The preparation of this compound:
-The specific preparation method may require further information, but in general, it can be synthesized by organic synthesis.
About safety information:
-The toxicity and danger data of this compound are limited, so appropriate safety measures should be taken in handling and handling, and laboratory safety procedures should be followed.
-Theoretically, this compound may be irritating and damaging to the eyes, skin and respiratory tract.
-Wear protective goggles, gloves, and a protective mask when using or handling the compound to ensure safe handling.
Please note that when performing chemical synthesis, ensure that you have the necessary experimental skills, laboratory equipment and safety knowledge, and follow relevant laws and regulations.
Last Update:2024-04-09 20:49:11